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Tag Archives: nhaa
APS 4CS Meeting 2017

APS 4CS Meeting 2017

The APS 4 Corners Section Meeting is held annually and will be hosted at Colorado State University on October 20th and 21st. Oliver was invited to present the group’s research on Structure and function of electrogenic sodium/proton antiporter membrane proteins.

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Cover of the Journal of General Physiology

Cover of the Journal of General Physiology

The article Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights made the cover image of the December issue of the Journal of General Physiology. Graduate student David Dotson is a joint first author on the paper.

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Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights

Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights

A new crystal structure of the Escherichia coli NhaA dimer reveals a previously unidentified salt bridge between two highly conserved residues at the putative binding site. The combination of structural data with molecular dynamics simulations yields new insights into the transport mechanism.

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