Tag 1 | Beckstein Lab

. . . . .
Tag Archives: open-data
AdK apo PMF

AdK apo PMF

The enzyme adenylate kinase (AdK) undergoes a large hinge-like motion. In 2009, we studied the conformational transition between open and closed E. coli AdK without substrate, i.e. “apo AdK”, with a variety of computational methods. As part of the study we also produced a free energy landscape (a potential of mean force or PMF) as a function of the two domain angles. Here we make the data of the underlying free energy landscape available to other researchers so that they can use them in their own research.

Comment Continue Reading →
Lipidbook

Lipidbook

Lipidbook is a public repository and database for force field parameters with a special emphasis on lipids, detergents, and similar molecules that are of interest when simulating biological membranes.

Continue Reading →